CVID :
B cells normal in numbers ; but decrease in IgG IgM and IgA
Rx : IV immunoglobulins
X-linked (Bruton) Agammaglobulinemia :
Rx : IVIG
SCID :
Combined so Both B and T cells - related to both : B cells : recurrent sinopulmonary infection as early 6 month. T cells : Candida , AIDS , PCP
Rx : BMT
IgA deficiency :
Rx : infections and use blood from igA-deficient donors or that has been washed.
Hyper IgE: skin infections with staph.
CGD:
lymph nodes with purulent material leaking out . Abnormal NBT testing .
- Recurrent sinopulmonary infections in adults
- Decreased response to Antigen stimulation of B cells .
- NORMAL amount of lymphoid tissues
Rx : IV immunoglobulins
X-linked (Bruton) Agammaglobulinemia :
- Male Children
- B cells and Lymphoid tissue are diminished
- Absence of the tonsils, adenoids , lymph nodes . T cell NORMAL
Rx : IVIG
SCID :
Combined so Both B and T cells - related to both : B cells : recurrent sinopulmonary infection as early 6 month. T cells : Candida , AIDS , PCP
Rx : BMT
IgA deficiency :
- sinopulmonary infections : Difference it also have Atopic diseases , Anaphylaxis to blood tranfusion when blood is given from a patient who has normal levels of IgA
- Sprue like condition with fat malabsorption
Rx : infections and use blood from igA-deficient donors or that has been washed.
Hyper IgE: skin infections with staph.
CGD:
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