Ataxia describes a lack of muscle control during voluntary movements, such as walking or picking up objects. A sign of an underlying condition, ataxia can affect movement, speech, eye movement and swallowing.
Persistent ataxia usually results from damage to your cerebellum — the part of your brain that controls muscle coordination. Many conditions can cause ataxia, including alcohol abuse, stroke, tumor, cerebral palsy and multiple sclerosis. An inherited defective gene also can cause ataxia.
Treatment for ataxia depends on the cause. Adaptive devices, such as walkers or canes, might help you maintain your independence. Physical therapy, occupational therapy and speech therapy also might help.
Causes-Damage, degeneration or loss of nerve cells in the part of your brain that controls muscle coordination (cerebellum), results in ataxia. Your cerebellum comprises two pingpong-ball-sized portions of folded tissue situated at the base of your brain near your brainstem. The right side of your cerebellum controls coordination on the right side of your body; the left side of your cerebellum controls coordination on the left.
Diseases that damage the spinal cord and peripheral nerves that connect your cerebellum to your muscles also may cause ataxia. Ataxia causes include:
Head trauma. Damage to your brain or spinal cord from a blow to your head, such as might occur in a car accident, can cause sudden-onset ataxia, also known as acute cerebellar ataxia.
Stroke. When the blood supply to a part of your brain is interrupted or severely reduced, depriving brain tissue of oxygen and nutrients, brain cells die.
Transient ischemic attack (TIA). Caused by a temporary decrease in blood supply to part of your brain, most TIAs last only a few minutes. Loss of coordination and other signs and symptoms of a TIA are temporary.
Cerebral palsy. This is a general term for a group of disorders caused by damage to a child's brain during early development — before, during or shortly after birth — that affects the child's ability to coordinate body movements.
Multiple sclerosis (MS). MS is a chronic, potentially debilitating disease that affects your central nervous system.
Chickenpox. Ataxia can be an uncommon complication of chickenpox and other viral infections. It may appear in the healing stages of the infection and last for days or weeks. Normally, the ataxia resolves over time.
Paraneoplastic syndromes. These are rare, degenerative disorders triggered by your immune system's response to a cancerous tumor (neoplasm), most commonly from lung, ovarian, breast or lymphatic cancer. Ataxia may appear months or years before the cancer is diagnosed
Tumor. A growth on the brain, cancerous (malignant) or noncancerous (benign), can damage the cerebellum.
Toxic reaction. Ataxia is a potential side effect of certain medications, especially barbiturates, such as phenobarbital, and sedatives, such as benzodiazepines. Alcohol and drug intoxication; heavy metal poisoning, such as from lead or mercury; and solvent poisoning, such as from paint thinner, also can cause ataxia.
Vitamin E or vitamin B-12 deficiency. Not getting enough vitamin E or vitamiB-12, because of the inability to absorb enough of the vitamin or other reasons, can lead to ataxia.
For some adults who develop sporadic ataxia, no specific cause can be found. This is known as sporadic degenerative ataxia, which can take a number of forms, including multiple system atrophy, a progressive, degenerative disorder.
Hereditary ataxias
Some types of ataxia and some conditions that cause ataxia are hereditary. If you have one of these conditions, you were born with a defect in a certain gene that makes abnormal proteins. The abnormal proteins hamper the function of nerve cells, primarily in your cerebellum and spinal cord, and cause them to degenerate. As the disease progresses, coordination problems worsen.
You can inherit a genetic ataxia from either a dominant gene from one parent (autosomal dominant disorder) or a recessive gene from each parent (autosomal recessive disorder). In the latter case, it's possible neither parent has the disorder (silent mutation), so there may be no obvious family history.
Different gene defects cause different types of ataxia, most of which are progressive. Each type causes poor coordination, but each has specific signs and symptoms.
Autosomal dominant ataxias
These include:
Spinocerebellar ataxias. Researchers have labeled more than 20 autosomal dominant ataxia genes, and the number is likely to continue to grow. Cerebellar ataxia and cerebellar degeneration are common to all types, but other signs and symptoms, as well as age of onset, differ depending on the specific gene mutation.
Episodic ataxia. There are seven recognized types of ataxia that are episodic rather than progressive — EA1 through EA7. EA1 and EA2 are the most common. EA1 involves brief ataxic episodes that may last seconds or minutes. The episodes are triggered by stress, being startled or sudden movement, and often are associated with muscle twitching.
EA2 involves longer episodes, usually lasting from 30 minutes to six hours, that also are triggered by stress. With this type of ataxia, you may experience dizziness (vertigo), fatigue and muscle weakness during your episodes. In some cases of episodic ataxia, symptoms resolve in later life.
Episodic ataxia doesn't shorten life span, and symptoms may respond to medication.
Autosomal recessive ataxias
These include:
Friedreich's ataxia. This, the most common hereditary ataxia, involves damage to your cerebellum, spinal cord and peripheral nerves. Peripheral nerves carry signals from your brain and spinal cord to your muscles. In most cases, signs and symptoms appear before the age of 25.
The rate of disease progression varies. The first indication generally is difficulty walking (gait ataxia). The condition typically progresses to the arms and trunk. Muscles weaken and waste away over time, causing deformities, particularly in your feet, lower legs and hands.
Other signs and symptoms that may develop as the disease progresses include slow, slurred speech (dysarthria); fatigue; rapid, involuntary eye movements (nystagmus); spinal curvature (scoliosis); hearing loss; and heart disease, including heart enlargement (cardiomyopathy) and heart failure.
Ataxia-telangiectasia. This rare, progressive childhood disease causes degeneration in the brain and other body systems. The disease causes immune system breakdown (immunodeficiency disease), which increases susceptibility to other diseases. It affects various organs.
Telangiectasias are tiny red "spider" veins that may appear in the corners of your child's eyes or on the ears and cheeks. Although they're characteristic of the disease, your child may not develop them. Delayed motor skill development, poor balance and slurred speech are typically the first indications of the disease. Recurrent sinus and respiratory infections are common.
Children with ataxia-telangiectasia are at high risk of developing cancer, particularly leukemia or lymphoma. Most people with the disease need a wheelchair by their teens and die in their teens or early 20s.
Congenital cerebellar ataxia. This type of ataxia results from damage to the cerebellum that's present at birth.
Wilson disease. People with this condition accumulate copper in their brains, livers and other organs, which can cause neurological problems, including ataxia.
Symptoms-Ataxia can develop over time or come on suddenly. Ataxia, a sign of a number of neurological disorders, may cause:--Poor coordination-Unsteady walk and a tendency to stumble-Difficulty with fine motor tasks, such as eating, writing or buttoning a shirt-Change in speech-Involuntary back-and-forth eye movements (nystagmus)-Difficulty swallowing
HOMOEOPATHIC REMEDIES
ALUMINA 200-Alumina is an excellent remedy for Ataxia. There is a staggering gait with heaviness or numbness of limbs. The person walks with uncertainty. The person can walk in daytime although in a staggering way but at night, he or she experiences a complete inability to walk. If he or she closes eyes, there is also a chance of falling down. Heaviness or numbness in lower limbs is often a symptom in such patients. They may also describe the symptom of a bandaged feeling in limbs while walking. Apart from walking, there is a problem in swallowing food too. The oesophagus feels constricted while swallowing at times with a feeling of a lump in throat. Excessive dry feeling in throat may also be present. The food passes down the oesophagus with great difficulty. Symptoms of extreme exhaustion, fatigue and lack of strength are also presented by patients. The patients usually has an increased sensitivity to cold air.
ARGENTUM NITRICUM 200-Argentum Nitricum is another top Homeopathic remedy with a marked action on the nervous system. There is marked loss of balance while walking and standing, along with trembling. The patient lacks control over his limbs while walking and experiences trembling. Standing and walking postures are quite unsteady. The unsteadiness mostly gets worse when the person is not under any observation. The frequent complaint accompanying unsteadiness is a marked rigidity in the calf muscles of the legs while walking. The muscles of legs also seem very weak while walking or standing.
CAUSTICUM 200- Causticum is another top remedy for ataxia. The person feels unsteady while walking and has frequent falling episodes. The fall can be sideways or forward. There is difficulty in articulation with an indistinct speech is also cured by Causticum.
GELSEMIUM 200-In Gelsemium the loss of muscle control is accompanied by excessively weak muscles. There is utmost lack of muscle coordination and the muscles seem not to obey the will of the patient. The gait is slow and unsteady. The person also feels tired from doing even the slightest work. The patient shows hallmark symptoms of drowsiness, dullness and dizziness with an inability to coordinate muscular action. Another symptom is difficulty in speech with trembling of tongue.
LATHYRUS SATIVUS 30—In Lathyrus Sativus there is tottering gait in Ataxia patients, who experience emaciation of muscles of lower limbs. Jerking and trembling while walking may also be symptoms described by the patient. There is also a marked rigidity of the legs while walking.
PLUMBUM MET 30-In Plumbum Met with atrophied muscles of legs, there is pain in legs. Plumbum Met is also of great help for Ataxia with difficulty in raising or lifting anything with hands.
HELODERMA 30- Heloderma is the best remedy for Ataxia patients who lift the feet higher than required while walking and bring them to the ground very hard. The patient may be extremely sensitive towards cold.
PHOSPHORUS 30-The various eye troubles faced by a person suffering from Ataxia are best covered by the remedy Phosphorus. This medicine can help to relieve symptoms of dim vision, blurred vision and also double vision. Easy fatigue of eye muscles even from a little use is also treated with Phosporus.
BELLADONNA 30- Belladona is the best remedy for a staggering, difficult and unsteady gait in the beginning stages. The muscular coordination is lacking.
NUX VOMIVA 30- In Nux Vomica is there is dragging of feet while walking, with an inability to lift the feet from ground. Nux Vomica is also the best medicine for Ataxia in alcoholics.
ZINCUM MET 30-In Zincum Met there is trembling and jerking of limbs accompany the lack of muscle coordination. The feet may show restlessness. Zincum Met is also the best remedy when pain in limbs is dominantly present in patients of Ataxia in the beginning stages.